Drug Discovery

MarketReports.com | Pharmaceuticals & Healthcare | Drug Discovery

High Throughput qPCR Assay Trends 2012
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Published: February 2012
Format: PDF
Pages: 51
Executive Summary and Table of Contents

This market report summarizes the results of HTStec’s global web-based benchmarking survey on high throughput real-time quantitative PCR (HT qPCR) assays carried out in January 2012.

The study was initiated by HTStec as part of its ongoing tracking of emerging life science technologies and marketplaces. The questionnaire was compiled to address the needs and interests of the HT qPCR vendor community.
The main objectives were to comprehensively document HT qPCR assay metrics, reagents and equipment used, and to understand future user requirements. For the purpose of this survey HT qPCR was defined as annually processing 250,000 or more qPCR assays per calendar year.
The report is a source of useful information for vendors developing HT qPCR instruments, assays or related products, and provides the latest market information about this rapidly changing area.

Label-Free Binding Analysis Trends 2012
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Published: January 2012
Format: PDF
Pages: 56
Executive Summary and Table of Contents

This market report summarizes the results of HTStec’s 3rd global web-based benchmarking survey on label-free (LF) binding analysis carried out in January 2012.

The study was initiated by HTStec as part of its bi-annual tracking of this life science marketplace. The questionnaire was compiled to address the needs and interests of the LF binding analysis vendor community.
The main objectives of this global benchmarking study were to comprehensively document current experience of and future interest in investigating biomolecular interactions and binding analysis using LF technologies. The study also examined in detail the market landscape, new application areas (including protein carbohydrate analysis) and throughput considerations.

The report is a valuable resource for vendors selling/developing LF binding analysis systems, and provides the latest market information about this rapidly changing area.
Equal emphasis was given to soliciting opinion from Pharma, Biotech and Academic Research segments, active in either small molecule drug discovery or protein and biologics characterization, in both North America and Europe.

Biomarkers in Drug Discovery - Earlier Usage of Biomarkers in Optimization Stage to Reduce Drug Attrition Rate Significantly

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Publication Date: 03-Oct-2011
Format: PDF
Pages: 103
Publisher: GBI Research
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GPCRs in Drug Discovery - Efforts to De-Orphanize Novel GPCR Targets are Increasing

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Publication Date: 01-Nov-2011
Format: PDF
Pages: 143
Publisher: GBI Research
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3D Cell Culture Trends 2011
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Published: November 2011
Format: PDF
Pages: 55
Executive Summary and Table of Contents

This market report summarizes the results of HTStec’s second industry-wide global web-based benchmarking survey on three dimensional (3D) cell culture carried out in October 2011.

The study was initiated by HTStec as part of its ongoing tracking of fast moving life science technologies and marketplaces and to update its previous report (published February 2010).
The main objectives of this study were to comprehensively document current interest in, experience of and progress made in applying 3D cell culture techniques in academic research, drug discovery and tissue engineering/regenerative medicine settings, and to understand their future requirements.

HCS Assays, Reagents & Consumables Trends 2011
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Published: October 2011
Format: PDF
Pages: 59
Executive Summary and Table of Contents

This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on high content screening (HCS) assays, reagents and consumables carried out in October 2011.

The study was initiated by HTStec as part of its ongoing tracking of emerging life science marketplaces. The questionnaire was compiled to meet the needs and interests of the cellular assay reagent and microplate vendor communities. The main objectives of this global benchmarking study were to comprehensively document current end user opinions, practices and preferences in HCS assays, reagents and consumables, and to understand future requirements.

Multi-Mode Microplate Reader Trends 2011
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Published: September 2011
Format: PDF
Pages: 66
Executive Summary and Table of Contents

This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on multi-mode microplate readers carried out in September 2011.

The study was initiated by HTStec as part of its ongoing tracking of emerging life science marketplaces. The questionnaire was compiled to address the needs and potential interests of the microplate instrument vendor community. The main objectives of this global benchmarking study were to comprehensively document current end user opinions, practices and preferences of multi-mode microplate readers, and to understand future requirements. Unlike previous updates the focus of this 2011 report was more on what influenced purchasing and new application areas, and less on reader technical specifications and filter versus monochromator-based instruments. The report is based on 144 responses from University Research Labs, Pharma and Biotech, mainly in North America and Europe.

Pathway Analysis (Signal Transduction) Trends 2011
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Published: September 2011
Format: PDF
Pages: 57
Executive Summary and Table of Contents

This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on pathway analysis (signal transduction) assays in drug discovery carried out in August 2011.

The study was initiated by HTStec as part of its ongoing tracking of emerging life science marketplaces. The questionnaire was compiled to meet the needs and interests of the cellular assay reagent vendor community. The main objectives of this global benchmarking study were to comprehensively document current end user opinions, practices and preferences in the pathway analysis (signal transduction) assays used in drug discovery, and to understand future requirements. The report is based on 120 responses from University Research Labs, Pharma and Biotech, mainly in North America and Europe.

Cell-Based Assays For Biologics Trends 2011
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Published: August 2011
Format: PDF
Pages: 55
Executive Summary and Table of Contents

This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on cell-based assays for biologics carried out in July 2011.

The study was initiated by HTStec as part of its ongoing tracking of emerging life science marketplaces. The questionnaire was compiled to meet the needs and interests of the cellular assay reagent vendor community. The main objectives were to comprehensively document current end user opinions, practices and preferences in the development of bioassays for large molecule (biologics) applications in drug discovery, and to understand future requirements. The report is based on 101 responses from University Research Labs, Pharma and Biotech, mainly in North America and Europe.

Stem Cells in Drug Discovery Trends 2011
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Price: $2,500.00 (€1,902.14) ($3,000.00 (€2,282.57) Including VAT at 20%)

Published: July 2011
Format: PDF
Pages: 62
Executive Summary and Table of Contents

This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on stem cells in drug discovery carried out in June 2011.

The study was initiated by HTStec as part of its ongoing tracking of emerging life science marketplaces. The questionnaire was compiled to meet the needs and interests of the stem cell vendor community. The main objectives were to comprehensively document current end user opinions, practices, and preferences for the use of stem cells in drug discovery applications and to understand future requirements. The report is based on 82 responses from University Research Labs, Pharma, and Biotech, mainly in North America and Europe.

Academic Outreach & Screening Trends 2011
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Price: $2,500.00 (€1,902.14) ($3,000.00 (€2,282.57) Including VAT at 20%)

Published: June 2011
Format: PDF
Pages: 77
Executive Summary and Table of Contents

This market report summarizes the results of HTStec’s global web-based benchmarking survey on academic outreach and screening carried out in June 2011.

The study was initiated by HTStec as part of its ongoing tracking of emerging life science technologies and marketplaces. The main objectives were to compile a report that comprehensibly documents the current status, capabilities, resources, budgets and interests of academic screening centers.

The report is intended as a reference/resource document that will facilitate identifying screening centers with certain capabilities or interests, and the direct comparison (benchmarking) of the screening centers surveyed. It is anticipated that the reports will be of interest to 3rd parties seeking comparative data and a concise summary of information on academic outreach and screening (e.g. Large Pharma looking for potential screening collaborators or other organizations and vendors that want to seek out centers).

Lead Generation Strategies and Technologies in Drug Development - Emerging Techniques Such as Antisense Technology Will Allow Innovators to Minimize Costs

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Publication Date: 10-Jun-2011
Format: PDF
Pages: 77
Publisher: GBI Research
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Small-Scale Benchtop Automation Trends 2011
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Price: $2,500.00 (€1,902.14) ($3,000.00 (€2,282.57) Including VAT at 20%)

Published: June 2011
Format: PDF
Pages: 52
Executive Summary and Table of Contents

This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on small-scale benchtop automation carried out in June 2011.
The main objectives of this global benchmarking study were to gain a better understanding of the current interest in and future market requirements for small-scale benchtop automated systems. Equal emphasis was given to soliciting opinion from all organisations types and intended application areas, with no geographic bias in the distribution of persons contacted.
The survey looked at the following aspects of small-scale benchtop automation as practiced today (2011) and in a few cases as predicted for the future (2014): familiarity and current use of automation; current views/thinking on small-scale benchtop automation; what is driving the implementation of small-scale benchtop automation; automation preferences; importance of walk-away automation; degree of flexibility required; key to making small-scale benchtop automation fully accessible and useful to the majority of potential end-users; interest in potential applications of a small-scale benchtop automation system (i.e. sample prep; PCR & next-gen sequencing; liquid dispensing; dose-response analysis; ELISA; aspects of cell maintenance; and cell-based assays); number of samples per batch; automated liquid dispensing requirements; type of vessels to be used; accessories that must be available as options; factors influencing vendor purchasing decision; level of awareness of some examples of small-scale benchtop automated systems; annual CAPEX budget for small-scale benchtop automation and breakdown between different instrument types; vendors most likely to be considered when purchasing in the near future; time frame to purchase a small-scale benchtop automation system and the reason for purchase; and unmet needs in small-scale benchtop automation today.

Advances in Drug-Diagnostic Co-Development Price: $3,835.00 (€2,917.89) ($4,602.00 (€3,501.46) Including VAT at 20%)
Publication Date: 05-May-2011 Please click here for more information or to purchase this report at our partner store To successfully market a targeted drug it is essential to have an associated diagnostic test toidentify the correct patients. As more targeted drugs are developed drug-diagnostic co-development is of increasing importance to pharma market growth.

Next-Gen Sequencing Trends 2011
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Published: Mar 2011
Format: PDF
Pages: 61
Executive Summary and Table of Contents

This market report summarizes the results of HTStec’s 2nd industry-wide global web-based benchmarking survey on next-generation sequencing (NGS) carried out in March 2011.
The study was initiated by HTStec as part of its ongoing tracking of emerging life science technologies and marketplaces. The main objectives were to comprehensively document current end-user experiences, practices, preferences, future requirements and assay metrics obtained using NGS machines, undertaking sample prep and automation for NGS, and outsourcing NGS. Equal emphasis was given to soliciting opinion from all organizations where NGS is currently being investigated, with no geographic bias in the distribution of persons contacted.

Drug Discovery and Preclinical Molecules by Therapy Area - Innovation Focuses on Stem Cell Therapies and Gene Therapies

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Publication Date: 10-Feb-2011
Format: PDF
Pages: 209
Publisher: GBI Research

“Drug Discovery and Preclinical Molecules by Therapy Area - Innovation Focuses on Stem Cell Therapies and Gene Therapies”, provides an in-depth analysis of the unmet needs, drivers and barriers that affect the global Central Nervous System Disorders (CNS), Metabolic Disorders, Immunologic Disorders, Infection, Cardiovascular Disease and Oncology therapeutic markets. The report analyzes the early stage drug development that includes drugs under development in the discovery and preclinical stages of development for the above mentioned indications in the US, the top five countries in Europe (the UK, Germany, France, Italy and Spain) and Japan. Treatment usage patterns, sales value and the annual cost of therapy are forecast until 2017 for the key geographies in the leading therapeutic segments. Further, the report provides competitive benchmarking for the leading companies and analyzes the Mergers and Acquisitions (M&A) and licensing agreements that shape the global market.

Preclinical Models - Preclinical CROs will Continue to Improve the Quality and Accuracy of Data for Targeted Therapies

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Publication Date: 01-Mar-2011
Format: PDF
Pages: 84
Publisher: GBI Research
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Ion Channel Screening Trends 2011
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Published: Mar 2011
Format: PDF
Pages: 67
Executive Summary and Table of Contents

This market report summarizes the results of HTStec’s seventh industry-wide global web-based benchmarking survey on ion channel screening carried out in February 2011.
The study was initiated by HTStec as part of its ongoing tracking of emerging life science marketplaces. The questionnaire was compiled to meet the needs of the ion channel screening vendor community.
The main objectives of this year’s study were to better understand respondent’s interest and experience of: 1) ion channels screened, assay technology used and screening metrics generated; 2) the use and purchase of automated patch clamp (APC) systems for ion channel screening; 3) cell requirements for ion channel assays; and 4) the use of outsourced ion channel testing services. Equal emphasis was given to soliciting opinion from Pharma, Biotech and Academic Research segments, in North America, Europe and Japan.

How IT Helps Solve Pharma's R&D Problems: in silico Drug Discovery Price: $3,395.00 (€2,583.11) ($4,074.00 (€3,099.73) Including VAT at 20%)
Publication Date: 06-Jul-2010 Please click here for more information or to purchase this report at our partner store Defining the role of technology to improve early stage R&D productivity

Innovative Drug Discovery in Emerging Markets Price: $3,835.00 (€2,917.89) ($4,602.00 (€3,501.46) Including VAT at 20%)
Publication Date: 13-Dec-2010 Please click here for more information or to purchase this report at our partner store This report assesses and documents the innovative drug discovery taking place in a corporate setting in countries that constitute emerging pharmaceutical markets (Brazil, Mexico, China, India, and Russia).

The Drug Discovery Outsourcing Market Price: $3,835.00 (€2,917.89) ($4,602.00 (€3,501.46) Including VAT at 20%)
Publication Date: 07-Jan-2011 Please click here for more information or to purchase this report at our partner store As large pharmaceutical companies seek to drive down fixed costs they are outsourcing an increasingly wide range of functions. Strong growth in drug discovery outsourcing will continue and the market is expected to exceed $18bn by 2015.

In Vivo Preclinical Imaging Trends 2011
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Published: Jan 2011
Format: PDF
Pages: 49
Executive Summary and Table of Contents

This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on in vivo preclinical imaging carried out in January 2011.
The questionnaire was compiled to meet the needs and interests of the in vivo imaging vendor community. The main objectives were to comprehensively document current practices and preferences on in vivo imaging used in preclinical drug development, and to understand future user requirements. The report is based on 76 responses from University Research Labs, Pharma, and Biotech, mainly in North America and Europe.

Diseased Primary Cells Trends 2010
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Published: Dec 2010
Format: PDF
Pages: 60
Executive Summary and Table of Contents

This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on diseased primary cells and in vitro models of disease carried out in November 2010.
The survey looked at the following aspects of diseased primary cells as practiced today (2010) and in some cases as predicted for the future (2013): the main advantages of using a diseased primary cells; the limitations of using primary cells; the key disease/therapeutic areas targeted and the most relevant primary cell types; current use of in vitro and in vivo models of disease; level of use of diseased primary cells; diseased primary cell types respondents would most like to use; main drug discovery applications targeted with diseased primary cells; obstacles related to the supply/generation of diseased primary cells; the source of diseased primary cells; companies most recognized as suppliers/providers of diseased primary cells; pattern of spending on primary cells; factors influencing the purchase of primary cells; interest in accessing primary cancer/tumor cells; preferred format to access diseased primary cells; in vitro characterization of diseased primary cells and clinical information required to ensure that isolated cells are suitable for use as a disease cell model; current use of induced pluripotent stem (iPS) cells; source of iPS cells; preferred stem cells lines; use of 3D-cell culture; main benefits of 3D-cell culture; awareness of any additional unmet needs in the area of diseased primary cells; and interest in receiving more information and beta-testing diseased primary or stem cells.

Top 10 Drug Discovery Technologies - Strategic Analysis and Global Forecasts

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Publication Date: Nov-2010
Format: PDF
Pages: 311
Publisher: MarketsandMarkets
Table of Contents
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The top 10 drug discovery technologies play a vital role in the growth of the entire pharmaceutical industry as they are the key contributors in the swift introduction of blockbusters and innovative drugs, which is the most important aspect for the pharmaceutical companies. The applications of these technologies in the introduction of drugs for diverse diseases such as cancer, CVD, CNS disorders such as Parkinson’s and Alzheimer’s and other serious chronic diseases have created significant opportunities for the market growth in the future. The slow growth of the introduction of new blockbuster drugs is a major concern which the drug development companies are catering to by using these top technologies.
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siRNA Screening Trends 2010
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Published: Nov 2010
Pages: 49
Executive Summary and Table of Contents

This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on siRNA screening carried out in October 2010.
The survey looked at siRNA screening as practiced today (2010) and in some cases as predicted for the future (2013). Specifically the following were investigated: level of interest in siRNA screening; current level of adoption of siRNA library screening in house; main application areas of siRNA library screening; what constitutes large-scale siRNA screening; final assay volume used for transfections; plate format mainly used for siRNA delivery (transfections) and screening; level of throughput achieved by in house siRNA screening programs; main endpoints (readouts) monitored when undertaking siRNA primary screening; cell types used for siRNA screening; preferred siRNA delivery methods; product names and main suppliers of transfection reagents and other silencing chemistries; source of the majority of the siRNAs that make-up respondent’s primary screening library; vendor compiled siRNA’s library groupings of greatest interest; species against which the majority of siRNAs are directed; size of libraries typically investigated in siRNA primary screens; main bottlenecks encountered in siRNA library screening; steps which most obstruct respondent’s ability to perform faster siRNA screening; main hurdles in siRNA sample preparation and liquid handling; extent to which automation has been applied to siRNA library screening; most important benefits of applying automation to siRNA screening; factors of greatest importance when choosing new automated instrumentation platform/tools for siRNA screening; product names and main suppliers of instrumentation (i.e. liquid handling, sample prep and automated assay platforms) used for siRNA screening; in house siRNA screening reagents budget and its breakdown into components; main suppliers of siRNA reagents; average cost per single target gene investigated by siRNA screening; level of interest in outsourcing siRNA library screening to a fee-for-service provider; and any unmet needs that exist in siRNA screening today.

GPCR Screening & Profiling Trends 2010
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Published: October 2010
Pages: 80

Executive Summary and Table of Contents

This market report summarizes the results of HTStec’s 4th industry-wide global web-based benchmarking survey on GPCR screening and profiling carried out in September 2010.

The main objectives were to better understand: 1) recent changes in GPCR assay metrics; 2) to comprehensively document current practices and technology preferences for GPCR primary screening and compound profiling; and 3) to understand future user requirements, particularly with respect to the need for new assays/approaches and outsourced services. The aim was to compile a reference document on GPCR screening and profiling metrics, which could be directly compared with previous HTStec reports.
The report is based on 85 responses from from Pharma, Biotech, Academic Screening Centers and University Research labs in both North America and Europe.

HTS Systems Reliability Trends 2010
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Published: September 2010
Pages: 54

Executive Summary and Table of Contents

This market report summarizes the results of HTStec’s vendor-independent global benchmarking study on HTS robotic assay system reliability carried out in September 2010.

The objective was to try to understand the impact of reliability of HTS systems on the company’s research enterprise as a whole and to see if it is possible to assign an economic value to the downtime of one of these HTS systems.

Adme/Tox Technologies
Price: $3,150.00 (€2,396.70) ($3,780.00 (€2,876.04) Including VAT at 20%)

Publication Date: Jan-2011
Format: PDF
Pages: 217
Publisher: RI Technologies
Table of Contents
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This market insight report on ADME/Tox Technologies covers both products and services used in the ADME/Tox industry. Predictive technologies analyzed include In vivo, In vitro, and In silico. Related technologies such as High Throughput Screening (HTS), and cell based assays are also analyzed. Market projections and estimates are illustrated by region and by technology. The report serves as a guide to ADME/Tox industry, covering 341 companies that are engaged in ADME/Tox studies/screening, products and services. Major Contract Research Organizations serving ADME/Tox industry are also covered in the corporate directory section of this report. Information related to recent product releases, product developments, partnerships, collaborations, and mergers and acquisitions is covered in the report. A global perspective is presented along with regional analysis covering the regions of North America, Europe, Asia-Pacific, Latin America, the Middle East and Africa with 145 exclusive graphically represented exhibits.

High Throughput Screening
Price: $3,250.00 (€2,472.79) ($3,900.00 (€2,967.34) Including VAT at 20%)

Publication Date: Jan-2011
Format: PDF
Pages: 264
Publisher: RI Technologies
Table of Contents
Sample Pages

This market insight report presents an in depth analysis of High Throughput Screening (HTS). The study emphasizes on both the technology and product segments of HTS in biotechnology and pharmaceutical application areas. The major technologies analyzed include Ultra High Throughput Screening, High Content/Cell Based Screening, Bioinformatics and Microfluidics/Lab-On-a-Chip; and the major product segments encompass HTS Services and HTS Tools. The global markets for Novel High Throughput Screening Products and Cell Based Assays are also discussed in the report. Markets covered for Microfluidics and Bioinformatics pertain to the applications of HTS. The report provides essential information including market data, segmentation, market size, key trends, M&A, product developments, industry forecasts, corporate intelligence, and other relevant information. The report lists 502 companies that are engaged in HTS services and/or production of HTS tools/instruments. Major Contract Research Organizations serving HTS industry are also covered in the corporate directory section of this report. Projections and estimates are graphically represented by region, by technology and by product segment. A global perspective is presented along with regional analysis covering the regions of North America, Europe, Asia-Pacific and Rest of World. The market is analyzed in US Dollars and includes 173 exclusive exhibits.

ELISA Trends 2010
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Published: August 2010
Pages: 53

Executive Summary and Table of Contents

This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on enzyme-linked immunosorbent assays (ELISA) carried out in August 2010.

The objective was to comprehensively document current practices and preferences in ELISA assays, and to understand future user requirements. Equal emphasis was given to soliciting opinion from all organizations where ELISA assays are currently being applied, with no geographic bias in the distribution of persons contacted.

Competitor Analysis: FGF-R Agonists and Antagonists

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Publication Date: 01-Nov-2009
Pages: 37
Publisher: La Merie

The present Competitive Intelligence Report about FGF-R agonists and antagonists provides a competitor evaluation in the field of fibroblast growth factor receptor (FGF-R) or PDGF targeting molecules for wound healing, cardiac tissue repair, bone formation or treatment of cancer as of November 2009. Purchase of the downloadable pdf report includes a 6-month online access to the data of the report and any updates since the publication date. Credentials to access the database will be sent by e-mail and allow online work with the project data to print or export an individual report.

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Competitor Analysis: Phosphodiesterase-4 (PDE-4) Inhibitors

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Publication Date: 09-Jan-2010
Pages: 24
Publisher: La Merie

The present Competitive Intelligence Report about PDE-4 Inhibitors provides a competitor evaluation in the field of small molecules specifically or unspecifically inhibiting phosphodiesterase 4 (PDE-4) as of January 2010. Purchase of the downloadable pdf report includes a 6-month online access to the data of the report and any updates since the publication date. Credentials to access the database will be sent by e-mail and allow online work with the project data to print or export an individual report.

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Biostorage Trends 2010
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Published: August 2010
Pages: 57

Executive Summary and Table of Contents

This market report summarizes the results of HTStec’s global web-based benchmarking survey on biological sample storage carried out in July 2010.

The objectives of the study were to comprehensively document current practices and preferences in biological sample storage and to understand future user requirements. Specifically the survey focused on the needs for deep-cooled (-20^oC and below) automated biosample storage and the requirements of software systems used for biosample tracking and the wider LIMS application.
Equal emphasis was given to soliciting opinion from academic & government laboratories; private & publicly-funded research organizations; and pharmaceutical & biotech companies. The majority of labs contacted were in North America and Europe.

Epigenetic Screening Trends 2010
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Published: June 2010
Pages: 54

Executive Summary and Table of Contents

This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on epigenetic enzyme screening assays carried out in June 2010.

The objectives were to comprehensively document current practices and preferences in epigenetic enzyme screening assays, and to understand future user requirements. Equal emphasis was given to soliciting opinion from Pharma, Biotech and Academic Screening/Research market segments in both North America and Europe.

Kinase Screening & Profiling Trends 2010
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Published: May 2010
Pages: 59

Executive Summary and Table of Contents

This market report summarizes the results of HTStec’s 4th industry-wide global web-based benchmarking survey on kinase screening and profiling carried out in April 2010.

The objective was to document current practices and preferences in kinase screening and profiling, and to understand future user requirements, particularly with respect to the need for outsourced services. The aim was to compile a reference document on kinase screening and profiling metrics, which could be compared relative to previous HTStec kinase reports. Equal emphasis was given to soliciting opinion from Pharma, Biotech and Academic/Research market segments in both North America and Europe.

qPCR Assay Trends 2010
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Published: April 2010
Pages: 52

Executive Summary and Table of Contents

This market report summarizes the results of HTStec’s 2nd industry-wide global web-based benchmarking survey on real-time quantitative PCR (qPCR) assays and instruments carried out in April 2010.

The study was initiated by HTStec as part of its ongoing tracking of emerging life science technologies and marketplaces. The main objectives were to comprehensively document current practices, preferences and trends in qPCR assays and instruments, and to understand future user requirements. Equal emphasis was given to soliciting opinion from all organizations where qPCR is currently being applied, with no geographic bias in the distribution of persons contacted.

The Future of GPCRs in Drug Discovery: Novel technologies, leading companies, and opportunities for target expansion
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Publication Date: 01-Apr-2010
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G-protein coupled receptors (GPCRs) constitute the largest, most ubiquitous, and most versatile family of membrane receptors. The benefits of each strategic approach are explored, and the role of specialist companies in their exploitation is highlighted. These specialist companies provide major companies with opportunities to develop new strategic partnerships and licensing opportunities to reinforce their pipelines.

Preclinical Models: Innovative solutions to accelerate drug discovery and development
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Publication Date: 10-Feb-2010
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This report explores novel preclinical models that demonstrate the potential to expedite and improve target validation and lead optimization timelines, and discusses the various advantages and disadvantages of absorption, distribution, metabolism and excretion toxicity (ADMET) screening technologies, to provide insight as to which models or systems may enhance R&D for pharmaceutical and biotechnology organizations. Additionally, it provides an outlook for preclinical testing over the next decade.

Drug Discovery in India and China - Gaining Momentum with Increasing Pressure on Cost Cutting

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Publication Date: 01-Feb-2010
Format: PDF
Pages: 107
Publisher: GBI Research
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Biomarkers in Drug Discovery - Optimizing Drug Discovery Timeline and Costs

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Publication Date: 01-Feb-2010
Format: PDF
Pages: 76
Publisher: GBI Research

'High drug attrition rates, time consuming methods and safety and efficacy concerns have encouraged the pharmaceuticals sector to adopt the use of biomarkers in the drug discovery process on a large scale'

According to the FDA, biomarkers are 10% more efficient in predicting drug failures and they can save approximately $100m and three to four years in each drug discovery process. The advantages of adopting the application of biomarkers in the drug discovery process is that they facilitate pharmaceutical companies to overcome the challenges posed by conventional drug discovery processes which are time consuming and expensive. Application of biomarkers in the pharmaceutical sector can revolutionize the drug discovery process by facilitating treatment decisions and the introduction of preventive and personalized medicines.

GBI Research's report "Biomarkers in Drug Discovery - Optimizing Drug Discovery Timeline and Costs" provides an in-depth analysis on the potential applications of biomarkers in pharmaceutical drug discovery and clinical services. The report supports investment decisions in biomarker based drug research by providing information on valid biomarkers, pipelines, case studies, competitive landscape, geographical dominance, mergers and acquisitions and market potential. It also provides an analysis on the trends prevailing in the global biomarkers market and also covers market drivers and restrains.
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Cellular Assay Reagents Trends 2009
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Published: February 2009
Pages: 75
Published by: HTStec Limited

Table of Contents

This market report summarizes the results of HTStec’s global web-based survey on Cellular Assay Reagents carried out in February 2009. The main objectives were to comprehensively document current use, interest and requirements for Cellular Assay Reagents as well as identifying emerging applications, market opportunities, unmet needs and demand for products.

Sample Preparation Trends 2009
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Price: $2,500.00 (€1,902.14) ($3,000.00 (€2,282.57) Including VAT at 20%)

Published: March 2009
Pages: 61
Published by: HTStec Limited

Table of Contents

This market report summarizes the results of HTStec’s global web-based survey on Sample Preparation Trends carried out in March 2009. The main objectives were to comprehensively document current use, interest and requirements for Sample Preparation as well as identifying emerging applications, market opportunities, unmet needs and demand for products.

Multi-Mode Microplate Reader Trends 2009
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Price: $2,500.00 (€1,902.14) ($3,000.00 (€2,282.57) Including VAT at 20%)

Published: March 2009
Pages: 56
Published by: HTStec Limited

Table of Contents

This market report summarizes the results of HTStec’s global web-based survey on Multi-Mode Microplate Reader trends carried out in March 2009. The main objectives were to comprehensively document current use, interest and requirements for Multi-Mode Microplate Readers as well as identifying emerging applications, market opportunities, unmet needs and demand for products.

Automated Solid Dispensing Trends 2009
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Price: $2,500.00 (€1,902.14) ($3,000.00 (€2,282.57) Including VAT at 20%)

Published: April 2009
Pages: 43
Published by: HTStec Limited

Table of Contents

The report summarizes the results of HTStec’s global web-based benchmarking survey on the automation of solid/powder dispensing carried out in April 2009. The main objectives were to comprehensively document current practices, preferences and trends in the automation of solid/powder dispensing in compound management facilities and in groups downstream. The report is based on 60 responses, obtained primarily from Pharma and Biotech, in North America and Europe.

1536 Progress Trends 2009
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Published: May 2009
Pages: 58
Published by: HTStec Limited

Table of Contents

HTStec's 1536 Progress Trends 2009 report summarizes the results of HTStec’s global web-based benchmarking survey on 1536 progress carried out in April 2009. The main objectives were to understand how widely 1536 plates have been adopted in drug discovery, what success has been achieved, which aspects are still problematic and what restricts its wider implementation. The report is based on 56 responses, obtained primarily from Large Pharma in North America and Europe.

Bulk Reagent Dispenser Trends 2010
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Price: $2,500.00 (€1,902.14) ($3,000.00 (€2,282.57) Including VAT at 20%)

Published: March 2010
Pages: 50

Report Sample of Contents [Click Here to Download PDF File]

HTStec's Bulk Reagent Dispenser Trends 2010 report was published on 22 March 2010. This 50 page report summarizes the results of HTStec's industry-wide global web-based benchmarking survey on bulk reagent dispensers (BRD's) carried out in February 2010. The main objectives of this study were to comprehensively document current end user experiences, practices, and opinions obtained using BRDs and to understand future requirements. An additional objective was to estimate the market size for BRDs and future market growth potential. The report is based on 264 responses, obtained from primarily University/Research Institutes, Pharma and Biotech in both Europe and North America

Ion Channel Trends 2009
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Price: $2,500.00 (€1,902.14) ($3,000.00 (€2,282.57) Including VAT at 20%)

Published: June 2009
Pages: 66
Published by: HTStec Limited

Table of Contents

This report summarizes the results of HTStec’s sixth annual global Pharma, Biotech and Academic Research web-based benchmarking survey on ion channels carried out in June 2009. The main objectives were to better understand respondent’s interest and experience of: 1) ion channels investigated, assay technologies and screening metrics; 2) automated patch clamping (APC) systems and in evaluating the new APC systems coming to the market; 3) future requirements for ion channel screening using human embryonic stem cells (HESC); and 4) outsourced ion channel testing services. The report is based on 119 responses, obtained primarily from Pharma, Biotech and Academic Research segments, in both North America and Europe.

Next-Gen Sequencing Trends 2009
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Price: $2,500.00 (€1,902.14) ($3,000.00 (€2,282.57) Including VAT at 20%)

Published: August 2009
Pages: 51
Published by HTStec Limited

Table of Contents

This report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on next-generation sequencing carried out in July 2009. The main objectives were to document current user experiences, practices, assay metrics and preferences obtained using next-gen sequencing instruments and to understand future requirements. The report is based on 106 responses, obtained primarily from University, Research Institute or Not-for-Profit Facilities in both Europe and North America

3D Cell Culture Trends 2010
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Price: $2,500.00 (€1,902.14) ($3,000.00 (€2,282.57) Including VAT at 20%)

Published: July 2009
Pages: 134

Table of Contents

HTStec's 3D Cell Culture Trends 2010 report was published on 15 February 2010. This 45 page report summarizes the results of HTStec's industry-wide global web-based benchmarking survey on three dimensional (3D) cell culture carried out in January 2010. The main objectives of this study were to comprehensively document current end user experiences, practices and opinions obtained when attempting 3D cell culture in basic research, drug discovery and tissue engineering & clinical research settings, and to understand their future requirements. The report is based on 142 responses, obtained from primarily University/Research Institutes and Biotech in both Europe and North America.

Primary Cells in Drug Discovery Trends 2009
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Price: $2,500.00 (€1,902.14) ($3,000.00 (€2,282.57) Including VAT at 20%)

Published: October 2009
Pages: 53
Published by HTStec Limited

Table of Contents

This report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on primary cells carried out in October 2009. The main objectives were to comprehensively document current end user opinions, practices, and preferences obtained using primary cells in drug discovery applications and to understand future requirements. The report is based on 220 responses, obtained primarily from University/Research Institute, Pharma and Biotech in both Europe and North America

Cell Based Label Free Detection Trends 2009
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Price: $2,500.00 (€1,902.14) ($3,000.00 (€2,282.57) Including VAT at 20%)

Published: December 2009
Pages: 53
Published by HTStec Limited

Table of Contents

HTStec's Cell-Based Label Free Trends 2009 report was published on 21 December 2009. This 53 page report summarizes the results of HTStec’s 2nd industry-wide global web-based benchmarking survey on cell-based label free (LF) detection carried out in December 2009. The main objectives were to comprehensively document current interest, application focus and future market requirements for cell-based LF detection. The report aims to be a source of valuable information for vendors developing novel cell-based LF detection systems and assays, and provides updated market intelligence in this rapidly emerging area. The report is based on 66 responses, obtained primarily from Pharma, Biotech and University/Research Institutes in both Europe and North America.

DOE in Assay Development Trends
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Price: $2,500.00 (€1,902.14) ($3,000.00 (€2,282.57) Including VAT at 20%)

Published: July 2009
Pages: 52
Published by: HTStec Limited

Table of Contents

This report summarizes the results of HTStec’s global Pharma, Biotech and Academic Research web-based benchmarking survey on the use of design of experiments (DOE) in assay development (AD) carried out in June 2009. The main objectives were to examine (1) how widely DOE approaches in AD are used; (2) what is the current level of understanding of DOE; (3) what views people hold about DOE and its benefits; (4) what success has been achieved; (5) which aspects of DOE are problematic; and (6) what restricts its wider implementation today. The report is based on 68 responses from 48 different organizations –primarily from Pharma, Biotech and Academic Research segments, in both North America and Europe.

Label Free Binding Analysis Trends 2010
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Price: $2,500.00 (€1,902.14) ($3,000.00 (€2,282.57) Including VAT at 20%)

Published: February 2010
Pages: 55

Report Table of Contents (TOC) [Click Here to Download PDF File]

HTStec's Label Free Binding Analysis Trends 2010 report was published on 15 February 2010. This 55 page report summarizes the results of HTStec's 2nd industry-wide global web-based benchmarking survey on label free (LF) binding analysis carried out in January 2010. The study aims to document the challenges faced when investigating biomolecular interactions and binding analysis using LF approaches; detail the current status with regard to the search/acquisition for new LF assay technologies; and to better understand future market needs within this area. The report is intended as a source of information for vendors developing novel LF binding analysis systems, and provides up to date market intelligence in this rapidly changing area. The report is based on 149 responses, obtained from primarily University/Research Institutes, Pharma and Biotech in both Europe and North America.

TR-FRET Based Assay Trends 2009
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Price: $2,500.00 (€1,902.14) ($3,000.00 (€2,282.57) Including VAT at 20%)

Published: December 2009
Pages: 51
Published by HTStec Limited

Table of Contents

HTStec's TR-FRET Based Assay Trends 2009 report was published on 14 December 2009. This 51 page report summarizes the results of HTStec’s 3rd industry-wide global web-based benchmarking survey TR-FRET (Time Resolved–Fluorescence Resonance Energy Transfer) based assays and reagents carried out in December 2009. The main objectives were to comprehensively document current practices, requirements and future trends for TR-FRET based assay reagent technologies. The questions were aimed at providing vendors with updated information on the use of TR-FRET based assays since the previous (December 2007) report and direction as to where they should focus their future R&D efforts on reagent technologies. The report is based on 52 responses, obtained primarily from Pharma, Biotech and University/Research Institute in both Europe and North America.

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